Cream progesterone vs oral – which is better?
Progesterone cream can be applied to the skin to relieve many symptoms associated with menopause. It is absorbed into the fat under the skin from where it goes straight into the blood stream from where it circulates to the rest of the body to carry out its effects. Relatively small doses such as those found in over-the-counter, non-prescription, bio identical progesterone creams can still be effective in relieving menopause symptoms.
When progesterone is taken by mouth, like everything else you swallow, it is absorbed into the blood and taken to the liver. Here more than 3/4 of it is removed and converted to an inactive form leaving only a small amount of progesterone to act in the body. This means that much larger doses are required to achieve the same effect as what you get from applying it to the skin.